Brain-Penetrating Drug Candidate Effective Against Deadly Encephalitis Viruses

A new antiviral compound designed and synthesized by researchers at the University of Wisconsin–Madison’s School of Pharmacy is highly effective in mice against two types of devastating encephalitis viruses that are harmful to humans.

UW–Madison School of Pharmacy’s Jennifer Golden Designs Promising New Compounds To Fight Deadly Mosquito-Transmitted Viruses

The School of Pharmacy makes a breakthrough in creating new small molecules that penetrate into the brain where the equine encephalitis viruses reside and interfere with viral replication to stop EEV. The research is funded by a new, five-year $21 million award from the National Institutes of Health (NIH).

Medicinal Chemistry Center Moves Drug Discovery Forward With Unparalleled Expertise

The early phase of drug discovery is seemingly straight-forward: screen molecules for biological activity, validate screening hits, design and synthesize novel drug molecules for testing in cells and animals. But while drug companies breeze through that process