Brain-Penetrating Drug Candidate Effective Against Deadly Encephalitis Viruses

A new antiviral compound designed and synthesized by researchers at the University of Wisconsin–Madison’s School of Pharmacy is highly effective in mice against two types of devastating encephalitis viruses that are harmful to humans.

UW–Madison School of Pharmacy’s Jennifer Golden Designs Promising New Compounds To Fight Deadly Mosquito-Transmitted Viruses

The School of Pharmacy makes a breakthrough in creating new small molecules that penetrate into the brain where the equine encephalitis viruses reside and interfere with viral replication to stop EEV. The research is funded by a new, five-year $21 million award from the National Institutes of Health (NIH).