{"id":54,"date":"2025-05-20T19:15:15","date_gmt":"2025-05-20T19:15:15","guid":{"rendered":"https:\/\/wwwtest.pharmacy.wisc.edu\/faculty\/kwon-research-group\/?page_id=54"},"modified":"2025-06-02T19:32:32","modified_gmt":"2025-06-02T19:32:32","slug":"nih-r21ca252579","status":"publish","type":"page","link":"https:\/\/wwwtest.pharmacy.wisc.edu\/faculty\/kwon-research-group\/research\/nih-r21ca252579\/","title":{"rendered":"Targeting Tumor Fibrosis with a Potent Peptide Inhibitor of Fibronectin Assembly"},"content":{"rendered":"","protected":false},"excerpt":{"rendered":"Grant information NIH R21CA252579 06\/01\/2021 \u2013 05\/31\/2023 The Kwon Research Group has developed PEG-FUD, a PEGylated peptide inhibitor of fibronectin assembly, by conjugating a 20-kDa PEG to the Functional Upstream Domain (FUD) peptide to enhance pharmaco-kinetics while preserving nanomolar binding affinity for fibronectin’s N-terminal 70-kDa domain critical for fibrillogenesis. Characterization via isothermal titration calorimetry and…","protected":false},"author":7,"featured_media":0,"parent":18,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-54","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/wwwtest.pharmacy.wisc.edu\/faculty\/kwon-research-group\/wp-json\/wp\/v2\/pages\/54","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wwwtest.pharmacy.wisc.edu\/faculty\/kwon-research-group\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/wwwtest.pharmacy.wisc.edu\/faculty\/kwon-research-group\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/wwwtest.pharmacy.wisc.edu\/faculty\/kwon-research-group\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/wwwtest.pharmacy.wisc.edu\/faculty\/kwon-research-group\/wp-json\/wp\/v2\/comments?post=54"}],"version-history":[{"count":6,"href":"https:\/\/wwwtest.pharmacy.wisc.edu\/faculty\/kwon-research-group\/wp-json\/wp\/v2\/pages\/54\/revisions"}],"predecessor-version":[{"id":286,"href":"https:\/\/wwwtest.pharmacy.wisc.edu\/faculty\/kwon-research-group\/wp-json\/wp\/v2\/pages\/54\/revisions\/286"}],"up":[{"embeddable":true,"href":"https:\/\/wwwtest.pharmacy.wisc.edu\/faculty\/kwon-research-group\/wp-json\/wp\/v2\/pages\/18"}],"wp:attachment":[{"href":"https:\/\/wwwtest.pharmacy.wisc.edu\/faculty\/kwon-research-group\/wp-json\/wp\/v2\/media?parent=54"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}