{"id":52,"date":"2025-05-20T19:14:47","date_gmt":"2025-05-20T19:14:47","guid":{"rendered":"https:\/\/wwwtest.pharmacy.wisc.edu\/faculty\/kwon-research-group\/?page_id=52"},"modified":"2025-06-11T16:32:56","modified_gmt":"2025-06-11T16:32:56","slug":"nih-r01ca257837","status":"publish","type":"page","link":"https:\/\/wwwtest.pharmacy.wisc.edu\/faculty\/kwon-research-group\/research\/nih-r01ca257837\/","title":{"rendered":"Oligolactic Acid Prodrug-Based Nanomedicines for Cancer Therapy"},"content":{"rendered":"","protected":false},"excerpt":{"rendered":"Grant information NIH R01CA257837 04\/01\/2021 \u2013 03\/31\/2025 The Kwon Research develops oligo(lactic acid) (o(LA)) prodrugs, such as o(LA)\u2088-paclitaxel (PTX), encapsulated in poly(ethylene glycol)-block-poly(lactic acid) (PEG-b-PLA) micelles to enhance drug delivery for triple-negative breast cancer (TNBC). o(LA)\u2088-PTX prodrug-loaded PEG-b-PLA micelles achieve high drug loading (up to 50% w\/w), prolonged plasma exposure (2-3\u00d7 higher AUC than non-prodrug…","protected":false},"author":7,"featured_media":0,"parent":18,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-52","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/wwwtest.pharmacy.wisc.edu\/faculty\/kwon-research-group\/wp-json\/wp\/v2\/pages\/52","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wwwtest.pharmacy.wisc.edu\/faculty\/kwon-research-group\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/wwwtest.pharmacy.wisc.edu\/faculty\/kwon-research-group\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/wwwtest.pharmacy.wisc.edu\/faculty\/kwon-research-group\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/wwwtest.pharmacy.wisc.edu\/faculty\/kwon-research-group\/wp-json\/wp\/v2\/comments?post=52"}],"version-history":[{"count":11,"href":"https:\/\/wwwtest.pharmacy.wisc.edu\/faculty\/kwon-research-group\/wp-json\/wp\/v2\/pages\/52\/revisions"}],"predecessor-version":[{"id":309,"href":"https:\/\/wwwtest.pharmacy.wisc.edu\/faculty\/kwon-research-group\/wp-json\/wp\/v2\/pages\/52\/revisions\/309"}],"up":[{"embeddable":true,"href":"https:\/\/wwwtest.pharmacy.wisc.edu\/faculty\/kwon-research-group\/wp-json\/wp\/v2\/pages\/18"}],"wp:attachment":[{"href":"https:\/\/wwwtest.pharmacy.wisc.edu\/faculty\/kwon-research-group\/wp-json\/wp\/v2\/media?parent=52"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}